Preliminary work towards CRISPR based gene drives in Lucilia cuprina - North Carolina State University

Australian sheep blowfly

Intended use

Reduction of disease and death of livestock caused by this species in Australia and New Zealand

Readiness of Technology

3 - Preliminary laboratory work published

Project leader

Scott MJ

Institution

North Carolina State University, USA

Publications

Authors name for system

NA – preliminary study only

Class of Technology

Not stated

Field(s) of application

Agriculture

Description of system

Probably homing CRISPR (in line with proposals for C. hominivorax)

Description

Propose gene drives targeting the Lctra gene which would disrupt female fertility.

Notes on readiness of technology

Protocols established for using CRISPR to modify genome

Phenotype

NA – preliminary study only

Authors name for construct(s)

NA – preliminary study only

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population suppression/eradication