Preliminary work towards a homing CRISPR gene drive in Polistes dominula - University of Edinburgh

European paper wasp

Intended use

Presumably to reduce biodiversity impacts of invasive populations of this species, however the authors do not make this explicit.

Readiness of Technology

2a - Gene drive proposed with supporting theoretical work

Project leader

Meiborg AB

Institution

Roslin Institute, University of Edinburgh, UK

Publications

Meiborg et al., 2023

Authors name for system

‘homing gene drive’ targeting a ‘haplosufficient female fertility gene’ [model other variants, but state this is the only candidate likely to be effective]

Class of Technology

Homing gene drive

Field(s) of application

Conservation

Description of system

Homing CRISPR

For specialists

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population suppression/eradication