Split homing CRISPR gene drive in Mus musculus - University of Adelaide

House mouse

Intended use

Suppressing/eradicating invasive rodents on islands, and reducing impacts of rodents on agriculture

Readiness of Technology

4b - research on gene drive construction has taken place but evidence so far shows this approach doesn't work

Project leader

Thomas PQ

Institution

University of Adelaide, Australia

Publications

Authors name for system

CRISPR-Cas9 based gene drive (test both ‘zygotic’ and ‘germline’ forms)

Class of Technology

Split homing gene drive

Field(s) of application

Conservation

Description of system

Split homing gene drive

Research in target organism

✔

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population suppression/eradication