Split homing CRISPR gene drive in Saccharomyces cerevisiae - Kansas State University

brewer’s or baker’s yeast

Intended use

To test various methods to modulate gene drive activity, e.g. Cas9 expression level (Roggenkamp et al. 2018) and Cas9 nuclear localisation (Goeckel et al. 2019).

Readiness of Technology

6 - Laboratory proof of concept

Project leader

Finnigan GC

Institution

Kansas State University, USA

Publications

Roggenkamp et al., 2018

Goeckel et al., 2019

Authors name for system

CRISPR-Cas9 gene drive / CRISPR gene drive

Class of Technology

Split homing gene drive

Field(s) of application

General research and development

Additional notes

It is uncertain if research has indeed progressed to the stage of laboratory proof of concept

Description of system

Split homing CRISPR

For specialists

Research in target organism

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Research in model organism

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Intended for release

✖

Intended direct effects

Population modification/replacement