'Z linked W-shredder' gene drive in Schistosoma genus - MIT & George Washington University

Blood fluke

Intended use

To suppress schistosome parasites to thereby reduce human morbidity and mortality from schistomiasis

Readiness of Technology

4a - Active research on gene drive construction

Project leader

Esvelt KM

Institution

MIT, USA

Project leader

Brindley P

Institution

George Washington University, USA

Publications

Authors name for system

One proposal would be a Z linked ‘W-shredder’ (as described by Holman, 2019); ‘all of the offspring will be born either female or male.’ (AAAS, 2016)

Class of Technology

Other gene drive system

Sex ratio distorter

Field(s) of application

Vector control

Additional notes

No results have been published

Description of system

Z linked W-shredder, with variable parameters (as described by Holman, 2019)

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population suppression/eradication