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Split homing CRISPR gene drive employing Cas12a in Saccharomyces cerevisiae - Kansas State University
Saccharomyces cerevisiae
brewer’s or baker’s yeast
Intended use
Proof of principle of population modification via a split homing gene drive based on Cas12a.
Readiness of Technology
6 - Laboratory proof of concept
Project leader
Finnigan GC
Institution
Kansas State University, USA
Publications
Lewis, Yan and Finnigan, 2021
Authors name for system
‘Cas12a-based gene-drive system’
Class of Technology
Split homing gene drive
Field(s) of application
General research and development
Additional notes
It is uncertain if research has indeed progressed to the stage of laboratory proof of concept
Description of system
Split homing CRISPR employing Cas12a
For specialists
Research in target organism
✖
Research in model organism
✖
Intended for release
✖
Intended direct effects
Population modification/replacement