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Tracking plans to genetically modify wild species
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‘X-shredder’ (I-PpoI based) in Anopheles coluzzii - Imperial College
Anopheles coluzzii
Intended use
Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)
Readiness of Technology
6 - Laboratory proof of concept
Project leader
Pollegioni P
Institution
National Research Council, Terni, Italy
Publications
Pollegioni et al., 2023
Authors name for system
‘synthetic sex ratio distortion transgene’
Class of Technology
Sex ratio distorter
Field(s) of application
Vector control
Description of system
Autosomal sex distorter -‘X-shredder’ (I-PpoI based)
For specialists
Research in target organism
✖
Research in model organism
✖
Intended for release
✖
Intended direct effects
Population suppression/eradication