Homing CRISPR gene drive for population modification in Anopheles coluzzii - University of Strasbourg

Intended use

Reduction of transmission of malaria pathogen by this vector (to reduce morbidity and mortality from malaria in Sub-Saharan Africa)

Readiness of Technology

5 - Limited proof of concept in laboratory

Project leader

Marois E

Institution

University of Strasbourg

Publications

Green et al., 2023

Authors name for system

'Saglin based gene drive'

Class of Technology

Toxin antidote gene drive

Homing gene drive

Field(s) of application

Vector control

Description of system

Homing gene drive variant - the homing gene drive element promotes inheritance of 'the antimalarial Lipophorin::Sc2A10 allele' at a second genomic loci

For specialists

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population modification/replacement