Split homing gene drive targeting Kmo in Aedes aegypti with multiplexed gRNAs - Pirbright Institute

Yellow fever mosquito

Intended use

Presumably population modification to reduce impacts on human health from transmission of pathogens by this vector species.

Readiness of Technology

5 - Limited proof of concept in laboratory

Project leader

Alphey L

Institution

Pirbright Institute, UK

Publications

Authors name for system

Split, multiplexed CRISPR/Cas9 gene drive system

Class of Technology

Split homing gene drive

Field(s) of application

Vector control

Description of system

Split homing gene drive targeting Kmo with multiplexed gRNAs

Research in target organism

✖

Research in model organism

✖

Intended for release

✖

Intended direct effects

Population modification/replacement