Gene Drive Projects
Select one or more options to filter by taxonomic groups.
Animalia
Chordata (incl. vertebrates e.g. mammals and birds)
Aves (birds)
Passeriformes (passerine birds)
Common starling
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Suppression to address ’impacts to biodiversity and agriculture’, however this species is noted for the damage it causes to crops so this is likely the primary driver
Type of system
Homing CRISPR
Amphibia (amphibians)
Anura (frogs and toads)
Caribbean tree frog
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Eradication or suppression of this species, (accepting risk of global extinction), to address biodiversity impacts of invasive populations.
Type of system
Homing CRISPR
Cane toad
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Suppression to address impacts on native species in Australia, which are either predated by toads or poisoned by eating them
Type of system
Homing CRISPR
Cane toad
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Suppressing ‘invasive populations of cane toads’
Type of system
Z linked W-shredder, with variable parameters
Cane toad
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
To 'detoxify' toads in Australia to address impacts on native species which are poisoned by eating them
Hyperoartia (jawless fish)
Petromyzontiformes (lamprays)
Sea lamprey
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Suppression or eradication of the lamprey from the North American Great Lakes to prevent this parasitic species damaging fish stocks
Type of system
Options proposed include: Split homing CRISPR ; ‘Y-Linked X-shredder’ ; Homing CRISPR ; Toxin Antidote
Sea lamprey
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Suppression or eradication of the lamprey from the North American Great Lakes to prevent this parasitic species damaging fish stocks
Type of system
Homing CRISPR
Sea lamprey
Readiness of Technology
2a - Gene drive proposed with supporting theoretical workPublications
Intended use
Suppression or eradication of the lamprey from the North American Great Lakes to prevent this parasitic species damaging fish stocks
Type of system
sex ratio distorter causing "daughterless" phenotype
Sea lamprey
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Suppression or eradication of the lamprey from the North American Great Lakes to prevent this parasitic species damaging fish stocks
Type of system
Various CRISPR based options proposed including ' A homing-type drive targeting lamprey sex-determining or gametogenic genes' and 'integrating daisy-chain architecture with small-molecule contrrol elements'
Mammalia (mammals)
Artiodactyla (Deer and related mammals)
Deer
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
To render the wild population immune to chronic wasting disease [by spreading PRNP null alleles]
Type of system
Homing CRISPR