Gene Drive Projects
Select one or more options to filter by taxonomic groups.
Animalia
Arthropoda (incl. insects and spiders)
Insecta (insects)
Diptera (true flies)
Glossinidae
Glossina
Tsetse flies
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Reduction in transmission of trypanosome parasites by this vector (to reduce occurrence of sleeping sickness in humans and livestock, esp. European cattle breeds.)
Type of system
NA – proposal only
Psychodidae (drain flies)
Lutzomyia (sand flies)
Sandfly
Readiness of Technology
2b - Gene drive proposed with preliminary laboratory work fundedPublications
Intended use
Reduction in transmission of Leishmania infantum by this vector (to reduce occurrence of visceral leishmaniasis disease)
Type of system
Homing CRISPR
Phlebotomus (old world sandflies)
Sandflies (old world)
Readiness of Technology
1 - Gene drive proposedPublications
Intended use
Reduction in transmission of Leishmania parasites by this vector (to reduce occurrence of leishmaniasis disease)
Type of system
NA - proposal only
Sarcophagidae (flesh fly)
Wohlfahrtia (flesh flies)
Spotted flesh fly
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
To reduce impacts on livestock health from myiasis caused by this parasitic fly species.
Type of system
Homing CRISPR
Tephritidae (fruit flies)
Anastrepha
Mexican fruit fly
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to fruit crops caused by this species
Type of system
Preliminary study only, but development of CRISPR methods in this species points towards CRISPR based gene drive design.
Bactrocera
Oriental fruit fly
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to vegetable, fruit and nut crops caused by this species
Type of system
CRISPR based gene drive
Oriental fruit fly
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to vegetable, fruit and nut crops caused by this species
Type of system
Preliminary study only, but development of CRISPR methods in this species points towards CRISPR based gene drive design.
Oriental fruit fly
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of damage to vegetable, fruit and nut crops caused by this species
Type of system
Preliminary study only, but development of CRISPR methods in this species points towards CRISPR based gene drive design
Olive fruit fly
Readiness of Technology
3 - Preliminary laboratory work publishedPublications
Intended use
Reduction of harm to olive harvests caused by this species
Type of system
Homing CRISPR
Ceratitis (includes the Mediterranean fruit fly)
Mediterranean fruit fly (or medfly)
Readiness of Technology
5 - Limited proof of concept in laboratoryPublications
Intended use
Reduction of damage to fruit crops caused by this species
Type of system
Autosomal sex ratio distorter 'X-shredder'